Table 2.
Percent bias, model-based standard errors (SE), and empirical standard errors (ESE) for four estimators for cumulative risk after ten rounds of screening for simulated data.
Moderate dependence | Strong dependence | |||||
---|---|---|---|---|---|---|
% Bias | SE | ESE | % Bias | SE | ESE | |
Scenario 1: Independent censoring, constant risk | ||||||
Discrete survival | −0.002 | 0.005 | 0.009 | |||
Population average | −0.009 | 0.003 | 0.005 | |||
Adjusted population average | 0.007 | 0.005 | 0.009 | |||
Censoring bias | −0.094 | 0.010 | 0.015 | |||
Scenario 2: Independent censoring, variable risk | ||||||
Discrete survival | −0.007 | 0.005 | 0.008 | −0.010 | 0.004 | 0.008 |
Population average | 5.209 | 0.003 | 0.005 | 20.552 | 0.003 | 0.005 |
Adjusted population average | 1.574 | 0.004 | 0.007 | 7.043 | 0.004 | 0.008 |
Censoring bias | −0.072 | 0.011 | 0.010 | −0.074 | 0.009 | 0.018 |
Scenario 3: Dependent censoring, variable risk | ||||||
Discrete survival | −4.708 | 0.004 | 0.005 | −11.376 | 0.004 | 0.005 |
Population average | 9.630 | 0.001 | 0.002 | 10.148 | 0.002 | 0.002 |
Adjusted population average | 3.576 | 0.003 | 0.004 | 3.940 | 0.003 | 0.004 |
Censoring bias | −0.809 | 0.013 | 0.010 | −4.435 | 0.011 | 0.007 |
Scenario 4: Dependent censoring, constant risk | ||||||
Discrete survival | −1.993 | 0.019 | 0.032 | −3.976 | 0.018 | 0.031 |
Population average | 0.696 | 0.003 | 0.006 | 0.709 | 0.003 | 0.006 |
Adjusted population average | 1.280 | 0.011 | 0.018 | 2.339 | 0.011 | 0.018 |
Censoring bias | −0.699 | 0.027 | 0.067 | −1.022 | 0.025 | 0.070 |