Table 2.
IL-2 | IL-2 +IL-4 |
IL-2+ SIINFEKL |
IL-2+IL-4 +SIINFEKL |
|
---|---|---|---|---|
IFN-γ single positive cells |
0.2±0.1 | 0.8±0.3** | 85.4±4.8 | 16.7±9.0## |
IL-13 single positive cells |
0.2±0.1 | 5.6±1.4** | 0.5±0.4 | 33.3±8.7## |
IFN-γ+ IL-13+ | 0 | 0.1 | 3.2±2.4 | 7.5±2.5## |
IFN-γ− IL-13− | 99.6±0.2 | 94±2.4** | 10.9±4.6 | 42.4±8.1## |
IFN-γ and IL-13 expression in CD8+ T cells differentiated in IL-2 or IL-2+IL-4. Intracellular staining of IFN-γ and IL-13 in CD8+ T cells with or without SIINFEKL re-stimulation. Data (mean±SEM) showing % positive cells were from at least 9 independent experiments.
p<0.01 compared to the IL-2 group,
p<0.01 compared to the IL-2+SIINFEKL group.