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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Lancet Neurol. 2013 Feb;12(2):207–216. doi: 10.1016/S1474-4422(12)70291-0

Figure 1. Original Dynamic biomarkers of the AD pathological cascade model – 2010.

Figure 1

Aβ amyloid is identified by CSF Aβ42 or PET amyloid imaging. Neuronal injury and dysfunction is identified by CSF tau or FDG-PET. Neurodegenerative atrophy is measured by structural MRI. Reproduced from Jack et al 18.