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. Author manuscript; available in PMC: 2013 Apr 10.
Published in final edited form as: J Gene Med. 2009 Oct;11(10):913–920. doi: 10.1002/jgm.1372

Fig. 3. Western blot detection of hGAA in tissues.

Fig. 3

Tissues analyzed 24 weeks following administration of the AAV vector to 12 month-old (18 months) or 3 month-old (9 months) GAA-KO mice. Three different proteins were detected, hGAA, lysosomal associated membrane protein 2 (LAMP-2), and glyceraldehyde 3-phosphate dehydrogenase (GAPDH). GAPDH served as a control to indicate equal loading of each lane. Heart from GAA-KO mice, following administration of the AAV2/8 vector (AAV) or mock treatment (PBS). Each lane represents an individual mouse. Controls were a PBS-injected, age-matched GAA-KO mice, and a C57BL/6 mouse (wildtype).