Skip to main content
. Author manuscript; available in PMC: 2013 Apr 10.
Published in final edited form as: J Gene Med. 2009 Oct;11(10):913–920. doi: 10.1002/jgm.1372

Table 1.

Correction of glycogen storage in GAA-KO mice.1

Vector Age at vector administration Quadriceps Gastrocnemius Diaphragm Heart
AAV-SPhGAApA 12 months 33%* 67% 84% 99%
3 months 2 75% 79% 91% 100%
AAV-MHCK7hGAApA 12 months 40%* 28% 48%* 95%
3 months 3 82% 36% 82% 98%
1

Reduction compared to sham-treated GAA-KO mice. Significant difference in older, versus younger, GAA-KO mice indicated

*

p<0.05.

2

Previously reported GAA-KO mice following administration of an equivalent number of AAV2/8 vector particles at 3 month of age [6].

3

Previously reported GAA-KO mice following administration of an equivalent number of AAV2/8 vector particles at 3 month of age [12].