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. Author manuscript; available in PMC: 2013 Apr 10.
Published in final edited form as: Clin Cancer Res. 2011 Sep 14;17(21):6702–6711. doi: 10.1158/1078-0432.CCR-11-0647

Figure 4. Correlations between the level of CD20 or CD59 on the surface of CLL cells and the CDC effect mediated by anti-CD20 antibodies with or without rILYd4.

Figure 4

(A) The extent of cell death induced by OFA correlated significantly with the MESF of CD20 on the CLL cell surface. When combined with rILYd4, the extent of cell death induced by OFA positively correlated with the level of CD20. (B) Sensitivity of CLL cells to CDC induced by OFA or RTX treatment correlated negatively with the MESF of CD59 on CLL cells.