Table 1.

Detection of MMP-9 at 10 nM in blood serum doped DMEM, cell growth medium.

Micelle[a]	MMP-9	Solution conditions[b]	Fluorescence lifetime, t (ns)
M1	-	20% serum	3.94 +/- 0.03
M1	+	20% serum	3.93 +/- 0.01
M1 + M2	-	20% serum	3.93 +/- 0.01
M1 + M2	+	20% serum	0.56 +/- 0.02
M1 + M2	+	no serum	0.59 +/- 0.01

^[a]Micelle concentrations for M1 and M2 are 0.1 μM, and 1 μM respectively, with respect to PPA concentration.

^[b]Micelles were incubated under these conditions at 37 °C for 24 hrs prior to measuring lifetimes. DMEM = Dulbecco's Modified Eagle Media. Detection of MMP in blood serum doped DMEM media via significant shortening in fluorescence lifetime indicating particle fusion upon cleavage of PPAs within M1 and M2.