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. 2013 Feb 9;5(3):514–524. doi: 10.1093/gbe/evt021

Table 1.

Comparison of Different Methods for Calculation of α (%) for Nonsynonymous Substitutions

Divergent Sites Neutral Standard Our Calculations
Parsch Calculations
Whole-Genome Data
Parsch et al. (2010) Gene Subset
Parsch et al. (2010) Gene Subset
Autosome X-Linked Autosome X-Linked Autosome X-Linked
Dmela Synonymous (4fold) sites 39.0 (37.8 to 40.2) 56.1 (53.8 to 58.3) 43.7 (20.5 to 62.7) 73.4 (65.5 to 79.7)
Dmela 8–30 in intron ≤65 nt 19.6 (16.7 to 22.1) 40.4 (34.0 to 46.4) 42.2 (−7.7 to 69.2) 74.1 (50.5 to 85.3)
Dmel–Dsecb Synonymous (4fold) sites 49.4 (48.6 to 50.2) 66.9 (65.4 to 68.3) 48.8 (30.3 to 63.9) 81.7 (76.8 to 85.8) 49.0 74.3
Dmel–Dsecb 8–30 in intron ≤65 nt 45.2 (43.8 to 46.7) 63.1 (59.6 to 66.3) 52.5 (27.0 to 69.0) 80.7 (64.3 to 88.1) 43.7 79.7

Note.—The method used in our analyses is marked in bold. Confidence intervals based on 1,000 bootstrap trials are shown in parentheses

aOnly differences fixed in the Drosophila melanogaster (Dmel) lineage are used.

bAll differences fixed between D. melanogaster (Dmel) and D. sechellia (Dsec) are used.