Fig. 8.

Effects of NaTC on cellular accumulation of BODIPY-verapamil, rhodamine 123, and rhodamine 6G. HEK293 (A), HEK/ABCB1 (B), and HEK/ABCB4 (C) cells were incubated with HEPES buffer containing 20 μM BODIPY-verapamil, 20 μM rhodamine 123, or 20 μM rhodamine 6G in the absence (control; open bars) or presence of 0.5 mM NaTC (filled bars) for 2 h at 37°C. Each bar represents the mean ± S.E. of three measurements. The absence of an error bar signifies an S.E. value smaller than the graphic symbol.