Fig. 4.

CB₁ antagonism inhibits neointima formation in apoE^−/− mice. A: Evans Blue/DAPI staining of carotid cross-sections and intimal nuclei quantification in apoE^−/− mice treated with vehicle or AM281 7 (n = 9) and 28 days (n = 7) postballooning. B–D: Morphometric analysis. E–F: Quantification of CD68- (E) and α-SMA-positive (F) areas 28 days postballooning. G: CD31 immunostaining of apoE^−/− mice treated with AM281 or vehicle 7 days postballooning. *P < 0.05, **P < 0.01 and ***P < 0.005 for two-group comparison.