TABLE 3.
Major products from the lipoxygenase catalyzed dioxygenation of a range of polyunsaturated fatty acids
| Substrate | Monohydroxy Product | Dihydroxy Product (conjugated diene) | Dihydroxy Product (conjugated triene) |
| ARA, 20:4n-6 | 15-HETE | 5,15-diHETE | 8,15-diHETE |
| EPA, 20:5n-3 | 15-HEPA | 5,15-diHEPA | 8,15-diHEPA |
| DPAn-6, 22:5n-6 | 17-HDPAn-6 | —a | 10,17-diHDPAn-6 |
| DPAn-3, 22:5n-3 | 17-HDPAn-3 | 7,17-diHDPAn-3 | —b |
| DHA, 22:6n-3 | 17-HDHA | 7,17-diHDHA | 10,17-diHDHA |
a
7,17-diHDPAn-6 was detected as a minor product only.
b
10,17-diHDPAn-3 not detected.