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Diabetes-induced aortic pathological changes, inflammation, oxidative stress, fibrosis at 3 months by H&E staining (a), immunohistochemical staining for the expression of CTGF (b), TNF-α (c)-(e) as index of inflammation, and 3-NT (d)-(f) as an index of oxidative damage. Data were presented as means ± SD (n = 4). *P < 0.05 versus control. Bar = 50 μM.
