TABLE 2.

CORRELATION BETWEEN BIOMARKERS IN SUBJECTS WITH COPD^*

Correlation	Log SP-D (n = 1,899)	Fibrinogen (n = 1,540)	Log IL-6 (n = 1,881)	Log IL-8 (n = 1,880)	Log TNF-α (n = 1,889)	Log CRP (n = 1,632)
Log CC16	0.16 (<0.0001)	−0.002 (0.93)	0.09 (0.0001)	0.06 (0.02)	−0.02 (0.32)	0.04 (0.09)
Log SP-D		0.03 (0.28)	0.03 (0.20)	0.03 (0.23)	0.02 (0.29)	0.01 (0.78)
Fibrinogen			0.10 (<0.0001)	0.02 (0.43)	0.03 (0.22)	0.38 (<0.0001)
Log IL-6				0.06 (0.01)	−0.05 (0.04)	0.23 (<0.0001)
Log IL-8					−0.03 (0.17)	0.06 (0.01)
Log TNF-α						0.04 (0.11)

Definition of abbreviations: CC16 = Clara cell secretory protein; COPD = chronic obstructive pulmonary disease; CRP = C-reactive protein; SP-D = surfactant protein D; TNF = tumor necrosis factor.

^*Pearson correlation coefficient (P value).