TABLE 3.

SIGNIFICANTLY ENRICHED TERMS FROM FUNCTIONAL ANNOTATION CLUSTERING^* PERFORMED ON GENES DEMONSTRATING DIFFERENTIAL METHYLATION BY CURRENT SYSTEMIC STEROID USE

GO Term	Process	Benjamini-Hochberg P Value
GO:0031224	Intrinsic to membrane	2.5 × 10−2
GO:0007599	Hemostasis	8.7 × 10−4
GO:0050878	Regulation of body fluid levels	2.6 × 10−3
GO:0050817	Coagulation	4.1 × 10−3
GO:0007596	Blood coagulation	4.1 × 10−3
GO:0048878	Chemical hemostasis	2.2 × 10−3
GO:0006873	Cellular ion homeostasis	3.2 × 10−2
GO:0055082	Cellular chemical homeostasis	3.5 × 10−2
GO:0050801	Ion homeostasis	4.0 × 10−2
GO:0042592	Homeostatic process	2.8 × 10−2
GO:0050865	Regulation of cell activation	4.1 × 10−3
GO:0002694	Regulation of leukocyte activation	7.9 × 10−3
GO:0051249	Regulation of lymphocyte activation	8.0 × 10−3
GO:0030595	Leukocyte chemotaxis	7.5 × 10−3
GO:0060326	Cell chemotaxis	9.7 × 10−3
GO:0050900	Leukocyte migration	1.4 × 10−2
GO:0055074	Calcium ion homeostasis	7.7 × 10−3
GO:0055066	Di-, trivalent inorganic cation homeostasis	1.1 × 10−2
GO:0006874	Cellular calcium ion homeostasis	1.4 × 10−4
GO:0055065	Metal ion homeostasis	1.5 × 10−2
GO:0030005	Cellular di-, trivalent inorganic cation homeostasis	1.5 × 10−2
GO:0007204	Elevation of cytosolic calcium ion concentration	1.7 × 10−2
GO:0006875	Cellular metal ion homeostasis	2.6 × 10−2
GO:0051480	Cytosolic calcium ion homeostasis	2.8 × 10−2
GO:0030003	Cellular cation homeostasis	3.9 × 10−2
GO:0051222	Positive regulation of protein transport	9.6 × 10−3
GO:0042330	Taxis	3.1 × 10−2
GO:0006935	Chemotaxis	3.1 × 10−2
GO:0002683	Negative regulation of immune system process	3.0 × 10−2
GO:0051250	Negative regulation of lymphocyte activation	4.0 × 10−2
GO:000758	Response to nutrient	3.0 × 10−2

^*Functional annotation clustering performed using the Database for Annotation, Visualization, and Integrated Discovery (DAVID) Bioinformatics Resources 6.7.