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(A) Absolute number of deaths and (B) adjusted case fatality rate among emergency medical services (EMS) encounters hospitalized with severe sepsis. Adjusted models include age, sex, Charlson Comorbidity Index, receiving hospital, and a pre-hospital clinical risk score for critical illness. A comparison with acute myocardial infarction and stroke is provided for context. Solid circles, severe sepsis; gray triangles, AMI; gray squares, stroke.
