Table 1.
Serotype distribution of S. pneumoniae isolates from children with acute otitis media by age group and potential vaccine coverige: 1994-2011
|
Serotype |
No. of isolates per age group |
Total no. (%) of particular serotype |
|||
|---|---|---|---|---|---|
| ≤ 2 y | > 2–5 y | ≤ 5 y | > 5 y - 14 y | ||
|
PCV7 serotypes | |||||
| 19 F |
17 |
7 |
24 |
2 |
26 (20.3) |
| 6 B |
8 |
9 |
17 |
3 |
20 (15.6) |
| 14 |
10 |
- |
10 |
1 |
11 (8.6) |
| 9 V |
5 |
3 |
8 |
3 |
11 (8.6) |
| 23 F |
5 |
4 |
9 |
1 |
10 (7.8) |
| 18 C |
1 |
1 |
2 |
1 |
3 (2.3) |
| Total no. |
46 |
24 |
70 |
11 |
81 (63.3) |
|
Other vaccine serotypes | |||||
| 19 A |
9 |
4 |
13 |
1 |
14 (10.9) |
| 3 |
2 |
3 |
5 |
1 |
6 (4.7) |
| 6 A |
1 |
2 |
3 |
1 |
4 (3.1) |
| 7 F |
1 |
1 |
2 |
- |
2 (1.6) |
| 1 |
- |
1 |
1 |
1 |
2 (1.6) |
| Total no. |
13 |
11 |
24 |
4 |
28 (21.9) |
|
Non-vaccine serotypes | |||||
| 15 B |
2 |
3 |
5 |
- |
5 (3.9) |
| 23 A |
2 |
1 |
3 |
- |
3 (2.3) |
| 11a |
- |
2 |
2 |
- |
2 (1.6) |
| 13,28b |
- |
1 |
1 |
1 |
2 (1.6) |
| 15 C |
- |
2 |
2 |
- |
2 (1.6) |
| 10a |
1 |
1 |
2 |
- |
2 (1.6) |
| 16/36/37b |
- |
- |
- |
1 |
1 (0.8) |
| 24/31/40b |
- |
1 |
1 |
- |
1 (0.8) |
| NTc |
- |
- |
- |
1 |
1 (0.8) |
| Total no. |
5 |
11 |
16 |
3 |
19 (14.8) |
|
Overall no. (%) |
64 (50.0) |
46 (35.9) |
110 (85.9) |
18 (14.1) |
128 (100.0) |
|
Percentage coverage rate of pneumococcal conjugate vaccines | |||||
| PCV7 |
71.9 |
52.2 |
63.6 |
61.1 |
63.3 |
| PCV10 |
73.4 |
56.5 |
66.4 |
66.7 |
66.4 |
| PCV13 | 92.2 | 76.1 | 85.5 | 83.3 | 85.2 |
a The strains were determined to serogroup.
b Expected to be serotypes/serogroups (Strains were positive only for one of the pooled sera).
c Non-typeable strains with Pneumotest-kit sera.