Table 1.
Polymer/5-ALA weight ratio (mg/mg) |
Drug contents (%, w/w)
|
Particle size (nm) |
||
---|---|---|---|---|
Theoretical | Experimental | |||
Empty NPs | 100/0 | 0 | 0.0 | 191 |
PEG-Chito-5-ALA NPs | 90/10 | 10 | 2.8 | 194 |
80/20 | 20 | 5.6 | 211 | |
60/40 | 40 | 9.3 | 219 |
Abbreviations: 5-ALA, 5-aminolevulinic acid; PEG-Chito-5-ALA NP, Polyethylene glycol-Chito-5-ALA nanoparticles; empty NPs, empty nanoparticles.