Table 5. Complications of gangrene, osteomyelitis, and bacteremia/endocarditis/septicemia/sepsis by diabetes status, major initial clinical diagnosis, and setting from 2005 through 2010.
Type of SSTI-associated complicationa | |||||||||
Gangrene | Osteomyelitis | Bacteremia/Endocarditis/Septicemia/Sepsis | |||||||
In Diabetic Individuals | In Non-diabetic Individuals | Differ-ence | In Diabetic Individuals | In Non-diabetic Individuals | Differ-ence | In Diabetic Individuals | In Non-diabetic Individuals | Differ-ence | |
Initial Diagnosis Setting and group of SSTIs | N (%) | N (%) | p-value | N (%) | N (%) | p-value | N (%) | N (%) | p-value |
Initially Diagnosed in Ambulatory Settings | |||||||||
Abscess/Cellulitis | 551 (0.43%) | 432 (0.04%) | <.01 | 1,783 (1.38%) | 3,995 (0.35%) | <.01 | 1,050 (0.81%) | 3,161 (0.28%) | <.01 |
Decubitus Ulcer | 1,239 (7.76%) | 372 (2.11%) | <.01 | 4,014 (25.13%) | 1,522 (8.62%) | <.01 | 1,273 (7.97%) | 735 (4.16%) | <.01 |
Surgical site infection & Device or Graft | 33 (0.46%) | 52 (0.14%) | <.01 | 241 (3.40%) | 972 (2.60%) | <.01 | 525 (7.40%) | 909 (2.43%) | <.01 |
Folliculitis, Impetigo, Furuncle, Mastitis & Other SSTIs | 113 (0.25%) | 159 (0.02%) | <.01 | 344 (0.77%) | 1,005 (0.14%) | <.01 | 269 (0.60%) | 1,309 (0.18%) | <.01 |
All SSTIs in subgroup | 1,936 (0.98%) | 1,015 (0.05%) | <.01 | 6,382 (3.25%) | 7,494 (0.39%) | <.01 | 3,117 (1.59%) | 6,114 (0.32%) | <.01 |
Initially Diagnosed in Inpatient Setting | |||||||||
Abscess/Cellulitis | 669 (5.29%) | 358 (0.86%) | <.01 | 1,183 (9.35%) | 1,535 (3.71%) | <.01 | 2,139 (16.90%) | 4,244 (10.25%) | <.01 |
Decubitus Ulcer | 803 (21.12%) | 172 (7.16%) | <.01 | 1,429 (37.59%) | 393 (16.35%) | <.01 | 1,116 (29.35%) | 861 (35.83%) | <.01 |
Surgical site infection & Device or Graft | 123 (1.65%) | 137 (0.51%) | <.01 | 598 (8.04%) | 1,812 (6.73%) | <.01 | 2,747 (36.93%) | 6,752 (25.06%) | <.01 |
Folliculitis, Impetigo, Furuncle, Mastitis & Other SSTIs | 76 (6.46%) | 62 (1.18%) | <.01 | 115 (9.78%) | 217 (4.13%) | <.01 | 189 (16.07%) | 510 (9.70%) | <.01 |
All SSTIs in subgroup | 1,671 (6.66%) | 729 (0.96%) | <.01 | 3,325 (13.26%) | 3,957 (5.21%) | <.01 | 6,191 (24.69%) | 12,367 (16.27%) | <.01 |
Complications are not mutually exclusive.