Table 1. Comparison of 2-week and 9-week co-administration of gentamicin with NMDI-1 on MPS I-H biochemical endpoints in Idua ^W392X mouse brain.

	% WT Iduronidase Activity		% GAG Reduction		% β-HexReduction		% β-Gluc Reduction
Treatment	2wks	9wks	2wks	9wks	2wks	9wks	2wks	9wks
Untreated	0.018%	0.020%	NA	NA	NA	NA	NA	NA
Gentamicin	0.15%	0.17%	32%	49%	11%	13%	35%	43%
Gent+NMDI1	0.60%	0.61%	91%	75%	18%	27%	56%	64%