Table 3.

Plasma NEFA levels before and after 48 h infusion in mice

Mouse and treatment	n	Time (h)	NEFA (μmol/l)	p value (vs SAL)
WT-SAL	8	0	415 ± 59	–
		48	372 ± 50	–
WT-OLE	7	0	605 ± 49	–
		48	1,212 ± 110	<0.001
KO-OLE	7	0	513 ± 72	–
		48	1,269 ± 340	<0.01
KO-SAL	6	0	504 ± 67	–
		48	350 ± 110	NS

Data are means ± SEM

p47^phox-knockout mice (KO) and their WT littermate controls were treated for 48 h with saline (SAL) or oleate (OLE, 0.4 μmol/min), to elevate plasma NEFA 1.5- to twofold