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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: J Autoimmun. 2013 Feb 19;41:60–71. doi: 10.1016/j.jaut.2012.12.006

Figure 6. OGT and CXCR3 promoters are demethylated in CD4+ T cells from women with active lupus.

Figure 6

DNA was isolated from CD4+ T cells of 13 women with active lupus (SLEDAI = 7.8±2), 6 women with inactive lupus (SLEDAI = 3.0±1.5) and 9 healthy women, then sonicated into ~500 bp fragments. Methylated fragments were affinity purified and quantitated by PCR as described in Materials and Methods. Differentially methylated regions of OGT (A) and CXCR3 (B) are numbered relative to the transcription start site. ** p ≤ 0.006, *** p ≤ 0.001.