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The estimated GFR decreases over time. The GFR of the overall cohort was 57 ml/min/1.73 m2, 54 ml/min/1.73 m2, 49 ml/min/1.73 m2, and 43 ml/min/1.73 m2 at 1, 5, 10, and 15 years, respectively. The effect is more pronounced in patients undergoing liver transplantation in the earlier period of the study (prior to the year 2000).
