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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Curr Opin Chem Biol. 2012 Dec 24;17(2):189–196. doi: 10.1016/j.cbpa.2012.11.019

Figure 2.

Figure 2

A schematic showing the Co(III) Schiff base complex, [Co(acacen)(L)2]+, that undergoes a dissociative exchange of the labile axial ligands and coordinates His residues [8,9]. Attachment of a targeting molecule, R, on the ancillary acacen chelate allows for selective inhibition of the protein of interest [8,11,12].