Table 1.
Comparison of demographic, clinical, and pathologic characteristics of subjects with normal and elevated NLR.
| Variable | Normal NLR n = 132 | Elevated NLR n = 28 | p-value |
|---|---|---|---|
| Male gender | 104 (79%) | 26 (93%) | 0.12 |
| Age in years (mean) | 55.5 | 55.1 | 0.87 |
| Etiology of Cirrhosis | |||
| HCV | 57 | 18 | 0.06 |
| HCV and Alcohol | 33 | 4 | 0.32 |
| Alcohol alone | 13 | 2 | 0.74 |
| HBV | 12 | 2 | 0.98 |
| Other | 17 | 2 | 0.53 |
| Mean total lymphocyte count (thousand per cubic millimeter) | 3.2 | 3.1 | 0.77 |
| Mean biochemical MELD score at diagnosis | 10 | 9 | 0.61 |
| Mean AFP at diagnosis (ng/dL) | 275 | 296 | 0.74 |
| Outside Milan criteria at diagnosis | 19 (14%) | 7 (25%) | 0.06 |
| Mean time on wait list (days) | 23 | 26 | 0.49 |
| Locoregional therapy prior to transplantation | 92 (70%) | 18 (64%) | 0.08 |
| Incidental HCC | 11 | 4 | 0.47 |
| T stage underestimated by pre-operative imaging | 6 | 2 | 0.63 |
| Poorly differentiated tumor on explant | 19 | 2 | 0.37 |
| Any tumor greater than 3cm in diameter | 58 | 8 | 0.15 |
| Mean number of tumors | 1.4 | 1.6 | 0.21 |
| Mean size of largest tumor (in cm) | 2.2 | 2.0 | 0.11 |
| Microvascular invasion | 20 (15%) | 5 (18%) | 0.77 |