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. 2013 Apr 1;2:140. doi: 10.1186/2193-1801-2-140

Table 1.

The probability of finding a drug in year 1–5 according to model 1 and 3

Cash-flow to discovery/year (million $)
n 0,5 1 3
Model 1 1 0,0350 0,0700 0,2100
2 0,0338 0,0651 0,1659
3 0,0326 0,0605 0,1311
4 0,0315 0,0563 0,1035
5 0,0304 0,0524 0,0818
Model 3 All 0,0376 0,0809 0,3365

A probability rate P of 7 10-8 compounds/$ and a constant cash-flow to the discovery activities of $0.5 m, $1 m and $3 m per year has been used. In model 3, the probability weighted amount of drugs that may be found.