Table 1.
sEPSCs | sIPSCs | |||
---|---|---|---|---|
mDisc1 | Frequency (Hz) | Amplitude (pA) | Frequency (Hz) | Amplitude (pA) |
WT ♂ | 1.1 ± 0.4 | 16.1 ± 3.7 | 2.4 ± 0.4 | 35.3 ± 5.6 |
Mutant ♂ | 1.8 ± 0.3 | 12.5 ± 1.0 | 1.3 ± 0.3* | 26.3 ± 4.1 |
WT ♀ | 1.2 ± 0.2 | 11.5 ± 0.8 | 1.8 ± 0.3 | 26.6 ± 3.2 |
Mutant♀ | 2.0 ± 0.7 | 11.1 ± 1.3 | 2.9 ± 0.6 | 26.8 ± 1.8 |
WT ♂+♀ | 1.2 ± 0.2 | 13.0 ± 1.4 | 2.0 ± 0.2 | 29.7 ± 2.9 |
Mutant ♂+♀ | 1.9 ± 0.3* | 12.2 ± 0.8 | 1.6 ± 0.3 | 26.4 ± 3.2 |
hDisc1 | ||||
WT ♂ | 1.0 ± 0.4 | 12.2 ± 1.3 | 2.7 ± 0.4 | 26.5 ± 1.6 |
Mutant ♂ | 3.9 ± 1.7* | 13.2 ± 1.8 | 4.1 ± 0.7 | 28.0 ± 2.7 |
WT ♀ | 2.0 ± 0.9 | 12.9 ± 1.2 | 5.6 ± 0.7 | 30.8 ± 4.7 |
Mutant ♀ | 2.9 ± 0.6 | 14.6 ± 1.6 | 5.0 ± 0.9 | 32.8 ± 3.9 |
WT ♂+♀ | 1.4 ± 0.4 | 12.5 ± 0.9 | 4.1 ± 0.5 | 28.6 ± 2.5 |
Mutant ♂+♀ | 3.3 ± 0.7* | 14.0 ± 1.2 | 4.4 ± 0.6 | 29.7 ± 2.2 |
Denotes p<0.05,
denotes male, and
denotes female.