. Author manuscript; available in PMC: 2014 Mar 1.

Published in final edited form as: Mayo Clin Proc. 2013 Feb 4;88(3):259–270. doi: 10.1016/j.mayocp.2012.11.006

Table 4.

Standardized regression coefficients examining the association between cardiorespiratory fitness and single and clustered metabolic syndrome components in men (n = 30,167) and women (n = 8,492)

	Cardiorespiratory Fitness (METs)
	Model 1				Model 2				Model 3
Men	R²	β	R² Change	P value	R²	β	R² Change	P value	R²	β	R² Change	P value
Waist circumference (cm)	0.32	−0.57	0.296	< 0.001	0.78	−0.14	0.012	< 0.001	0.78	−0.13	0.010	< 0.001
Triglycerides (mg/dL) ^a	0.15	−0.41	0.150	< 0.001	0.18	−0.29	0.053	< 0.001	0.23	−0.26	0.040	< 0.001
HDL-cholesterol (mg/dL) ^b	0.13	0.34	0.106	< 0.001	0.17	0.25	0.038	< 0.001	0.18	0.23	0.031	< 0.001
Fasting blood glucose (mg/dL) ^a	0.06	−0.18	0.029	< 0.001	0.09	−0.09	0.005	< 0.001	0.14	−0.05	0.002	< 0.001
Systolic blood pressure (mmH g) ^a	0.06	−0.11	0.011	< 0.001	0.11	0.00	0.000	0.782	0.16	0.02	0.000	0.007
Diastolic blood pressure (mmHg)	0.07	−0.20	0.035	< 0.001	0.12	−0.07	0.003	< 0.001	0.17	−0.05	0.002	< 0.001
zMS	0.20	−0.37	0.121	< 0.001	0.38	−0.11	0.008	< 0.001	0.42	−0.08	0.004	< 0.001
Women
Waist circumference (cm)	0.22	−0.45	0.172	< 0.001	0.71	−0.04	0.001	< 0.001	0.71	−0.03	0.001	< 0.001
Triglycerides (mg/dL) ^a	0.14	−0.30	0.073	< 0.001	0.18	−0.17	0.017	< 0.001	0.21	−0.15	0.014	< 0.001
HDL-cholesterol (mg/dL) ^b	0.11	0.24	0.049	< 0.001	0.19	0.08	0.004	< 0.001	0.20	0.07	0.003	< 0.001
Fasting blood glucose (mg/dL) ^a	0.06	−0.10	0.008	< 0.001	0.09	0.01	0.000	0.336	0.12	0.04	0.001	0.006
Systolic blood pressure (mmHg) ^a	0.16	−0.13	0.014	< 0.001	0.21	−0.01	0.000	0.604	0.26	0.01	0.000	0.456
Diastolic blood pressure (mmHg)	0.10	−0.16	0.021	< 0.001	0.14	−0.05	0.001	< 0.001	0.20	−0.04	0.001	0.006
zMS	0.27	−0.27	0.063	< 0.001	0.44	−0.05	0.002	< 0.001	0.48	−0.03	0.001	0.002

Values were natural log-transformed before analysis.

Values were square root transformed before analysis.

Model 1: Adjustment for age, examination year;

Model 2: Adjustment for age, examination year, BMI, smoking (current smoker or not), alcohol intake (>14 drinks/week for men and >7 for women or not) and family history of cardiovascular disease;

Model 3: Adjustment for age, examination year, BMI, physical activity (active or inactive), smoking (current smoker or not), alcohol intake (>14 drinks/week for men and >7 for women or not), hypercholesterolemia, hypertension and diabetes (present or not for each), and family history of cardiovascular disease.