Table 2.

Ability of mutants to compete with ES114 in symbiotic infections and cocultures

Strain	Disrupted gene	RCI in squid (48 h)a	RCI/generationb
			In squid	In culturec
SLV41	arcA	0.49	0.98	0.90
NL3	arcB	0.25	0.95	0.93
EMH12	topA	0.03	0.89	<0.05
SLV32	lonA	0.02	0.88	0.96
SLV10	pstA	0.12	0.93	0.78
SLV30	pstC	0.04	0.90	0.78
SLV15	hns	<0.05	<0.05	<0.05
EMH7	tRNAMet	0.55	0.98	0.86
NL4	tRNAThr	0.63	0.99	0.90
NL1	tfoY	0.48	0.98	1.02
SLV16	phoQ	0.30	0.96	0.94
EMH5	guaB	0.40	0.97	0.93
NL2	ainS	NDd	ND	0.95

^aAll data were calculated for ≥10 animals.

^bEstimated by assuming 30 generations for 48 h in the squid host, which was previously published as a high estimate under these conditions (15).

^cCoculture data were collected from cultures grown in SWTO (n = 2).

^dND, not done (results were published previously [21]).