Table 4.

Univariable analysis for the prediction of Gleason upgrading in potential active surveillance patients

Predictors of upgrading	Univariable analyses
	OR	95% CI on OR	P value	PA; %
Preop PSA (continuous)	1.17	1.08, 1.27	<0.0001	59.0
Clinical stage (t2 vs. t1)	0.76	0.34, 1.70	0.4990	50.5
Biopsy cores (≥18 vs. <18)	0.97	0.60, 1.55	0.8853	50.2
Positive cores (2 vs. 1)	2.08	1.52, 2.84	<0.0001	58.0
Max % Bx (>5% vs. ≤5%)	1.44	1.07, 1.93	0.0152	54.5
HGPIN Bx (yes vs. no)	1.23	0.78, 1.93	0.3731	51.1
Prostate volume (continuous)	0.99	0.99, 1.00	0.0796	54.3

PA predictive accuracy (AUC from c-statistic)