Table 9.

Multivariable analysis for the prediction of worsening prognosis in potential active surveillance patients

Predictors of worsening prognosis	P value	Adjusted OR	95% C.I. for OR
			Lower	Upper
Preop PSA	<0.0001	1.239	1.132	1.357
Clinical stage	0.575	0.785	0.338	1.825
Biopsy cores	0.800	1.065	0.654	1.735
Positive cores	<0.0001	1.934	1.379	2.710
Max % Bx	0.343	1.168	0.848	1.609
HGPIN Bx	0.304	1.289	0.794	2.094
Prostate volume	0.010	0.990	0.982	0.998

PA = 64.4%; Preop PSA: Continuous in model; Clinical stage: t2 versus t1 (referent); Biopsy cores: ≥18 cores versus <18 cores (referent); Positive cores: 2 positive cores versus 1 positive core (referent); Max % Bx: >5% (median) versus ≤5% (referent); HGPIN Bx: yes versus no (referent); Prostate volume: Continuous in model