Table 1.
Clinical data and CSF characteristics of patients in the three study groups at baselinea
| Parameter | Value |
||
|---|---|---|---|
| Controls (n = 5) | EVDViv group (n = 3) | EVDVcomb group (n = 4) | |
| Age (yr) | 46 ± 17 | 48 ± 14 | 48 ± 12 |
| Sex (no. of males/no. of females) | 4/1 | 1/2 | 3/1 |
| Weight (kg) | 82 ± 10 | 84 ± 16 | 86 ± 11 |
| Creatinine (mg/dl) | 1.2 ± 0,5 | 1.2 ± 0.4 | 1.3 ± 0.8 |
| SOFA score | 8 ± 4 | 7 ± 2 | 7 ± 1 |
| APACHE II score | 22 ± 6 | 22 ± 6 | 20 ± 4 |
| GCS | 8 ± 4 | 7 ± 1 | 9 ± 4 |
| CSF characteristics | |||
| WBC (cells/μl) | 3 ± 2 | 344 ± 395 | 13,650 ± 15,415 |
| Glu (mg/dl) | 79 ± 25 | 22 ± 19 | 17 ± 16 |
| Pr (mg/dl) | 64 ± 60 | 228 ± 123 | 305 ± 145 |
a
Data are presented as means ± SD or as otherwise indicated. EVDViv, external ventricular drainage-associated ventriculitis patients treated with i.v. colistin; EVDVcomb, external ventricular drainage-associated ventriculitis patients treated with combined i.v. and intraventricular colistin; SOFA, sequential organ failure assessment; APACHE, acute physiology and chronic health evaluation; GCS, Glasgow coma scale; WBC, white blood cell; Glu, glucose; Pr, protein.