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Hemolytic potentials of various AmB-loaded nanocarriers and commercial formulations at different drug concentrations
| Concn (μg/ml) | % Hemolysisa |
|||
|---|---|---|---|---|
| NET-AmB | CNC-AmB | AmBisome | Fungizone | |
| 0.25 | 0.167 ± 0.34 | 0.029 ± 0.21 | 0.087 ± 0.18 | 0.973 ± 0.72 |
| 5 | 0.639 ± 0.24 | 0.552 ± 0.41 | 0.537 ± 0.19 | 1.986 ± 0.84 |
| 10 | 2.439 ± 0.54 | 1.973 ± 0.94 | 2.313 ± 0.89 | 10.816 ± 1.02 |
| 25 | 7.832 ± 1.67 | 3.291 ± 0.82 | 5.321 ± 1.02 | 100 |
Data are reported as means for 3 independent experiments ± SD.
