Table 1.

IC₅₀s for solithromycin inhibition in three organisms

Parameter	IC50 (ng/ml)a in:
	S. pneumoniae ATCC 49619	S. aureus RN1786 (MSSA)	S. aureus A1024 (MRSA)	H. influenzae G-79
Growth rate	7.5	40	52	125
CFU	7.5	80	85	125
Protein synthesis	7.5	40	48	125
50S subunit assembly	14.5	65	93	230
30S subunit assembly	>20	85	>100	>250

^aIC₅₀s were calculated from the results shown in Fig. 1a to d and 2a to d.