Table 2.
Vancomycin trough levels measured at 96 h after commencing treatment (n = 102)a
| Characteristic (n) | Median vancomycin trough level, mg/liter (IQR) | P value |
|---|---|---|
| Susceptibility | 0.784 | |
| MSSA (15) | 17 (15–23) | |
| MRSA (87) | 20 (15–24) | |
| Vancomycin MIC | 0.323 | |
| Low (59) | 19 (15–23) | |
| Elevatedb (43) | 21 (15–27) | |
| 30-day mortality | 0.729 | |
| Survivors (85) | 19 (15–23) | |
| Nonsurvivors (17) | 21 (16–26) |
a
Excludes 80 patients for whom the vancomycin trough level was drawn at other time periods or not drawn at all. Abbreviations: IQR, interquartile range; MSSA, methicillin-susceptible Staphylococcus aureus; MRSA, methicillin-resistant Staphylococcus aureus.
b
Elevated vancomycin MIC defined as an Etest value of >1.5 mg/liter.