Fig 1.

Data from in vitro competition experiments with E. coli MG1655 carrying the recombinant plasmids pBGS18-TEM1, pBGS18-SFO1, pBGS18-AmpR-SFO1, pBGS18-OXA10-like, pBGS18-FOX4, and pBGS18-CTX-M-32. The strains expressing AmpR-SFO1, OXA10-like, and OXA24 β-lactamases showed significant fitness costs. The CI values obtained with different β-lactamases are plotted and are representative of eight different experiments, with the median CI values shown by horizontal lines. (Adapted from reference 34.)