Table 1.
Demographic and clinical characteristics
| Variable | Value for group |
P valuea | |||
|---|---|---|---|---|---|
| Chronic HCV, no cirrhosis (n = 35) | Chronic HCV, cirrhosis (n = 40) | Alcohol/NASH cirrhosis (n = 21) | Uninfected, no cirrhosis (n = 22) | ||
| Age, yr (mean ± SD) | 57.0 ± 8.8 | 60.8 ± 4.7 | 60.0 ± 6.2 | 58.4 ± 7.6 | 0.06c |
| Gender, no. (%) | |||||
| Female | 2 (5.7) | 1 (2.5) | 0 (0.0) | 1 (4.5) | 0.76b |
| Male | 33 (94.3) | 39 (97.5) | 21 (100.0) | 21 (95.5) | |
| Ethnicity, no. (%) | |||||
| Caucasian | 19 (54.3) | 26 (65.0) | 17 (81.0) | 15 (68.2) | 0.49 |
| Black | 10 (28.6) | 8 (20.0) | 1 (4.8) | 4 (18.2) | |
| Other | 6 (17.1) | 6 (15.0) | 3 (14.3) | 3 (13.6) | |
| Hepatocellular carcinoma, no. (%) | |||||
| Yes | 0 (0.0) | 7 (17.9) | 3 (14.3) | 0 (0.0) | 0.006b |
| No | 35 (100.0) | 32 (82.1) | 18 (85.7) | 22 (100.0) | |
| BMI (mean ± SD) | 27.2 ± 4.6 | 28.4 ± 4.36 | 29.2 ± 6.3 | 29.3+-5.2 | 0.40c |
| Alcohol, no. (%) | |||||
| Yes | 2 (5.9) | 16 (41.0) | 17 (81.0) | 5 (22.7) | <0.0001 |
| No | 32 (94.1) | 23 (59.0) | 4 (19.0) | 17 (77.3) | |
| ATP (ng/ml), median (IQR) | 432 (366.2–552.1) | 256.7 (176.5–425.5) | 392.1 (280.3–519.4) | 456.3 (301.6–726.8) | 0.0001c |
| ALT (U/liter), median (IQR) | 40 (26–64) | 67 (39–96.5) | 23 (15–35) | 27 (20–52) | <0.0001c |
a
P values were calculated from the chi-square test for category variables and ANOVA for continuous variables unless otherwise indicated.
b
P values were calculated from Fisher's exact test.
c
The variable was rank transformed.