Fig 1.

Trial 1 local and systemic lymphoproliferative responses: PBMC or cells from the MRLN were incubated with intimin (medium-gray bars), ovalbumin (dark-gray bars), concanavalin A (white bars), and TCGF (light-gray bars) as positive controls to determine lymphoproliferative responses to proteins. (A) PBMC from week 0, prior to immunization; (B) cells from MRLN at week 9; (C) PBMC from week 9. Asterisks indicate significant responses of cells incubated with antigen compared to cells incubated with medium by a one-tailed Student t test at P values of <0.05 and SI greater than 2.0.