Fig 4.

Trial 3 lymphoproliferative responses in draining and contralateral PLN: cells from the lymph node draining the subcutaneous immunization site (left PLN) and contralateral lymph node (right PLN) were harvested 3 days after final immunization at week 11, incubated with intimin (medium-gray bars), ovalbumin (dark-gray bars), or concanavalin A (white bars) as a positive control to determine lymphoproliferative responses to proteins. (A) Cells from draining PLN; (B) cells from contralateral PLN. Asterisks indicate significant responses of cells incubated with antigen compared to cells incubated with medium by a one-tailed Student t test at P values of <0.05 and SI greater than 2.0.