Table 1.
Baseline characteristics of the study population
| Characteristic | Vildagliptin group | Control group | P |
|---|---|---|---|
| n | 15 | 15 | – |
| Males (n) | 12 (80.0%) | 15 (100.0%) | 0.07 |
| Age (years) | 58.6 ± 6.0 | 61.2 ± 8.3 | 0.43 |
| Body weight (kg) | 83.3 ± 10.8 | 88.3 ± 13.6 | 0.33 |
| Post-HTx (years) | 4.9 ± 5.3 | 7.2 ± 6.6 | 0.38 |
| Ischemic time (min) | 228.5 ± 82.2 | 221.7 ± 65.3 | 0.67 |
| Duration of diabetes (years) | 6.3 ± 3.6 | 5.6 ± 3.5 | 0.51 |
| Type 2 diabetes | 10 (66.7%) | 7 (46.6%) | 0.27 |
| pre-HTx (n) | |||
| Metformin therapy (n) | 6 (40%) | 7 (46.7%) | 0.71 |
| Insulin therapy (n) | 9 (60.0%) | 9 (60.0%) | – |
| HbA1c (%) | 7.4 ± 0.7 | 7.0 ± 0.7 | 0.09 |
| FPG (mg/dL) | 135.1 ± 31.2 | 145.9 ± 47.4 | 0.89 |
| MBG (mg/dL) | 165.0 ± 18.8 | 154.7 ± 19.7 | 0.09 |
| Creatinine (mg/dL) | 1.3 ± 0.5 | 1.5 ± 0.5 | 0.20 |
| Urea (mg/dL) | 54.7 ± 25.7 | 60.4 ± 25.7 | 0.61 |
| Triglycerides (mg/dL) | 216.0 ± 94.0 | 211.1 ± 125.1 | 0.86 |
| Cholesterol (mg/dL) | 177.5 ± 25.7 | 186.5 ± 73.2 | 0.82 |
| HDL (mg/dL) | 42.5 ± 7.3 | 39.3 ± 10.5 | 0.21 |
| LDL (mg/dL) | 93.7 ± 22.7 | 93.6 ± 38.3 | 0.89 |
| Hemoglobin (g/dL) | 12.4 ± 1.2 | 13.4 ± 1.8 | 0.19 |
| WBC (n/nL) | 7.3 ± 1.7 | 7.4 ± 2.2 | 0.73 |
| Platelets (n/nL) | 259.4 ± 50.9 | 224.9 ± 55.1 | 0.08 |
| CK (U/L) | 104.0 ± 37.1 | 127.4 ± 76.9 | 0.30 |
| LDH (U/L) | 227.5 ± 77.8 | 249.7 ± 86.4 | 0.73 |
| GOT (U/L) | 18.6 ± 7.7 | 24.9 ± 8.8 | 0.04 |
| GPT (U/L) | 19.2 ± 10.6 | 29.7 ± 15.7 | 0.12 |
| AP (U/L) | 89.1 ± 37.2 | 90.7 ± 23.6 | 0.57 |
| γGT (U/L) | 61.4 ± 63.7 | 106.6 ± 93.5 | 0.24 |
| NT-proBNP (ng/L) | 762.7 ± 1063.8 | 1277.8 ± 2572.0 | 0.93 |
| hs-TNT (pg/mL) | 14.2 ± 14.2 | 13.9 ± 16.0 | 0.88 |
Note: Data shown are the mean ± standard deviation unless otherwise indicated.
Abbreviations: AP, alkaline phosphatase; CK, creatine kinase; FPG, fasting plasma glucose; GOT, glutamic oxaloacetic transaminase; GPT, glutamic pyruvic transaminase; HbA1c, glycated hemoglobin; HDL, high-density lipoprotein; hs-TNT, high-sensitivity troponin T; HTx, heart transplantation; LDH, lactate dehydrogenase; LDL, low-density lipoprotein; MBG, mean blood glucose; NT-proBNP, N-terminal pro-brain natriuretic peptide; WBC, white blood cells; γGT, gamma-glutamyltransferase.