Table 5.
Case reports for trigeminal pain
| Gender /case number | Age | Primary diagnosis (pain indication/cause of pain/type of pain) | Localization of pain symptoms/predominantly intra-or extraoral | Duration of pain in years | Hyper-algesia | Allodynia/allodynia severity rating | Pain intensity (0–10) | Characteristics of pain | Mono-therapy | Plasters per day | Duration of plaster treatment (months) | CGIC score | 
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Trigeminal neuralgia | ||||||||||||
| M T4  | 
76 | Trigeminal neuralgia Intermittent pain | Left V1 Extraoral  | 
0.19 | X | 2 | 9 | Stabbing | N | 1/8 | 1.17 | 1 | 
| Ma T26  | 
82 | Trigeminal neuralgia type 2 Continuous pain | Right V1,2,3 Extraoral  | 
20 | X | 3 | 8–10 | Burning | N | 1/2 | 0.93 | 1 | 
| M T27  | 
53 | Trigeminal neuralgia Intermittent pain | Right V Extraoral  | 
3 | X | 2 | 5 | Stabbing | Y | 1/2 | 0.93 | 1 | 
| F T2  | 
62 | Trigeminal neuralgia type 2 Continuous pain with intermittent flares | Left Extraoral  | 
3 | 7 | Burning, shooting | N | 1/2 | NA | 2 | ||
| F T6  | 
29 | Trigeminal neuralgia Intermittent pain | V2 Extraoral  | 
0.5 | X | 1 | 7 | Shooting | N | 1/2 | 0.75 | 2 | 
| Ma T24  | 
35 | Trigeminal neuralgia Intermittent pain | Left V2 Extraoral  | 
3 | 2 | 8 | Shooting | N | 1/4 | 3 | 2 | |
| F T18  | 
62 | Trigeminal neuralgia type 2 Continuous pain with intermittent flares | Right V2,3 Extraoral, mainly intraoral  | 
14 | 2 | 8 | Stabbing, shooting, aching | N | 1/2 | 0.25 | 4 | |
| M T1  | 
75 | Trigeminal neuralgia Intermittent pain | Left V2,3 Extraoral  | 
5 | 8 | Stabbing, shooting | N | 1/2 | 2 | 4 | ||
| M T3  | 
80 | Trigeminal neuralgia Intermittent pain | Left V2,3 | ≥5 | 1 | 9 | Stabbing, shooting | Y | 1/2, not daily | <0.03 | 5 | |
| F T23  | 
82 | Neuralgia SUNCT Continuous pain with intermittent flares | Left V1,2,3 Extraoral  | 
5 | 1 | 7 | Burning, sharp, aching, dull | N | 1 | 1 | 4 | |
| Trigeminal neuropathic pain following surgery for trigeminal neuralgia | ||||||||||||
| F T17  | 
53 | Neuropathic pain Continuous pain | Right V2,3 Intra- and extraoral  | 
12 | 2 | 10 | Shooting, sharp | Y | 1/2 | 9 | 1 | |
| F T21  | 
49 | Neuropathic pain Continuous pain | Right V2,3 Extraoral  | 
2 | 2 | 8 | Burning | N | 1 weekly | 1 | 3 | |
| F T11  | 
64 | Bilateral neuropathic pain Intermittent pain | Right V2,3 Extraoral  | 
3 | 1 | 8 | Shooting, hot, pricking | N | 1/2 | 0.17 | 3, sleep improved | |
| Fa T7  | 
35 | Neuropathic pain Continuous pain with intermittent flares | V2,3 Extraoral | 2 | 2 | 8 | Burning, shooting | N | 1/2 | 0.7 | 3 | |
| F T12  | 
72 | Dysesthesia Continuous pain with intermittent flares | Left V3 Extraoral  | 
7 | 2 | 8 | Heavy, gripping | N | 1/2 | 0.25 | 4 | |
| M T16  | 
75 | Dysesthesia Continuous pain | Left V2,3 Extraoral  | 
25 | 1 | 8 | Burning, soreness, nagging, numbness | Y | 1 | 3 | 4 | |
| Trigeminal neuropathic pain following trauma | ||||||||||||
| F T13  | 
50 | Trigeminal posttraumatic neuropathic pain Continuous pain | Left V2 Extraoral  | 
1.5 | 2 | 9 | Burning, tingling, pricking | N | 1/2 | 4 | 2 | |
| F T22  | 
65 | Trigeminal neuropathic pain Continuous pain with intermittent flares | Left V1,2,3 Extraoral  | 
3 | 1 | 8 | Burning, shooting, throbbing, drilling, heavy, piercing | N | 1 every 2nd day  | 
7 | 2 sleeps better | |
| F T15  | 
63 | Neuropathic pain after extractions Continuous pain with intermittent flares | Right V3 Intraoral Extraoral  | 
3 | 7 | Shooting, cutting, aching, throbbing | N | 1/2 | 3 | 2 | ||
| M T20  | 
44 | Trigeminal neuropathic pain after dental extractions Continuous pain with intermittent flares | Right V1,2,3 Extraoral  | 
4 | 1 | Burning, sharp, dull | N | 1 every 2nd day  | 
0.5 | 4 | ||
| Trigeminal neuropathic pain following postherpetic neuralgia | ||||||||||||
| F T10  | 
45 | Postherpetic neuralgia Continuous pain with intermittent flares | Right V1 Extraoral  | 
2.5 | 1 | 10 | Stabbing, searing, burning, shooting, dull | N | 1/2 | 3 | 2 | |
| M T8  | 
78 | Postherpetic neuralgia Continuous pain with intermittent flares | Right V1 Extraoral  | 
0.25 | 2 | 7 | Burning | N | 1/4 | 3 | 2 | |
| F T14  | 
74 | Postherpetic neuralgia Continuous pain | Left V1 Extraoral  | 
1.67 | 4 | Burning, itchy, hot, numb, tingling | Y | Intermittent | 4 | 2 | ||
| F T19  | 
76 | Postherpetic neuralgia pain and burning mouth syndrome Continuous pain with intermittent flares | Right V2 Intra- and extraoral  | 
2 | 1 | 9 | Burning, drilling | N | 1/2 | Few weeks | 3 | |
Notes: Pain was initiated by triggers if not otherwise stated.
no triggers. Allodynia severity rating: 0 = no pain or discomfort to touch, 1 = uncomfortable, but tolerable to touch, 2 = painful, 3 = extremely painful, patient cannot stand touching; duration of pain was converted to years, term “many years” was set to ≥5 years in the table and to 5 years for calculation of means.
Abbreviations: CGIC, Clinical Global Impression of Change rating during treatment with 5% lidocaine-medicated plaster: 1 = very much improved, 2 = much improved, 3 = minimally improved, 4 = no change, 5 = minimally worse; F, female; M, male; NA, not available; N, no; SUNCT, short unilateral neuralgiform pain with conjunctival tearing; V1, ophthalmic; V2, maxillary; V3, mandibular; X, symptom present; Y, yes.