Table 3.
BPND for [11C]prucalopride in rat brain regions versus cerebellum
| Brain region | Baseline | Tariquidar pre-treatment |
|---|---|---|
| Striatum |
0.00 ± 0.08 |
0.07 ± 0.09** |
| Hippocampus |
−0.05 ± 0.05 |
0.07 ± 0.05* |
| Frontal cortex |
0.04 ± 0.07 |
0.03 ± 0.04 |
| Posterior cortex | 0.00 ± 0.05 | 0.03 ± 0.04 |
BPND for [11C]prucalopride in rat brain regions, at baseline and following pre-treatment with tariquidar (n = 4 for both conditions). Significant difference compared with baseline: *p < 0.05, **p < 0.01.