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. 2006 Mar 8;26(10):2788–2797. doi: 10.1523/JNEUROSCI.4331-05.2006

Figure 6.

Figure 6.

Inhibition of GABAB IPSCs by opioids and 5-CT from identified BLA- and NAc-projecting neurons. AC, Normalized summary data and typical recordings of GABAB IPSCs illustrating the effects of U69593 (200 nm; A), ME (3 μm; B), and 5-CT (100 nm; C) on BLA- (○) and NAc- (•) projecting VTA neurons (n = 6–8). Illustrated GABAB IPSCs are the averages of two to four traces before and during drug application. IPSCs were evoked with monopolar glass electrodes by a train of five pulses (duration, 0.5 ms; 40 Hz) every 60 s. The calibration in the middle panel of C applies to all traces from NAc-projecting cells; the calibration in the right panel of C applies to all traces from BLA-projecting cells. Error bars indicate SEM. * signifies significance at p < 0.05. NLX, Naloxone.