TABLE I.

Results of FBAT, MQLS, and LODPAL Analyses

Marker	cM	LOD	Informative families—FBAT	FBAT P-value	MQLS P-value	Major/minor Allelea	Nucleotide	Allele freq.		Gene
								Affected	Unaffected
rs7522166	164.75	0.089	23	0.629	0.233	2	C	0.478	0.523	COPA
rs12745476	167.01	0.024	18	0.709	0.529	1	C	0.774	0.785	SDHC
rs2819318	168.15	0.033	21	0.779	0.554	1	C	0.552	0.560	NOS1AP
rs1509024	170.13	0.435	27	0.148	0.250	1	G	0.724	0.705	NUF2
rs1387389	173.39	1.771	25	0.455	0.344	1	C	0.687	0.723	PBX1
rs7517175	174.66	2.676	27	0.366	0.129	1	T	0.537	0.504	UCK2
rs12076250	176.07	3.250	24	0.135	0.152	1	C	0.600	0.547	GPA33
rs1229355	177.46	3.193	26	0.915	0.979	1	T	0.542	0.563	RCSD1
rs3820403	178.71	3.471	20	0.220	0.834	1	A	0.629	0.593	TBX19
rs10800382	179.46	3.459	30	0.238	0.376	1	A	0.582	0.516
rs12143193	180.03	3.262	19	0.205	0.367	1	T	0.684	0.642	NME7
rs603246	180.76	2.876	26	0.609	0.400	1	G	0.612	0.591	KIFAP3
rs913257	181.51	2.926	25	0.851	0.477	1	A	0.498	0.523	FLJ11752
rs1920142	182.01	2.660	25	0.359	0.409	2	C	0.343	0.356	C1orf129
rs2272810	182.46	2.557	26	0.864	0.458	2	A	0.490	0.485	BAT2D1
rs2208370	182.79	2.572	17	0.726	0.842	1	G	0.612	0.623	DNM3
rs1063412	183.12	2.650	29	0.970	0.302	1	T	0.525	0.609	PIGC
rs10489273	183.53	2.916	24	0.676	0.584	1	G	0.570	0.557
rs10912624	183.86	2.817	20	0.501	0.599	1	T	0.780	0.797	SLC9A11
rs6678286	184.23	3.048	19	0.248	0.227	1	A	0.721	0.764	RABGAP1L
rs4650666	184.62	2.589	21	0.014	0.802	1	A	0.610	0.617	RABGAP1L
rs860907	185.00	2.390	26	0.992	0.199	1	G	0.622	0.650	TNR
rs4409605	185.58	2.212	29	0.382	0.836	1	A	0.580	0.590	RFWD2
rs6425386	186.10	2.039	22	0.480	0.316	2	T	0.403	0.377	PAPPA2
rs10798463	186.22	2.032	27	0.559	0.620	1	A	0.704	0.728	PAPPA2
rs7528287	186.33	2.034	30	0.587	0.323	1	G	0.620	0.663	PAPPA2
rs6413830	186.44	2.035	22	0.828	0.365	1	G	0.597	0.547	ASTN1
rs2281180	186.47	2.035	17	0.677	0.852	1	C	0.830	0.862	ASTN1
rs6680908	186.47	2.035	7	NA	0.227	1	C	0.910	0.937	ASTN1
rs974299	186.49	2.035	28	0.248	0.105	1	C	0.525	0.469	ASTN1
rs4652208	186.52	2.035	27	0.426	0.321	2	C	0.498	0.457	ASTN1
rs227987	186.53	2.035	27	0.185	0.074	1	T	0.530	0.472	ASTN1
rs228008	186.56	1.943	26	0.012	0.001	1	G	0.652	0.547	ASTN1
rs6668092	186.57	1.874	25	0.021	0.002	1	C	0.637	0.532	ASTN1
rs172917	186.58	1.826	29	0.027	0.003	1	G	0.652	0.547	ASTN1
rs10798496	186.58	1.826	28	0.128	0.002	1	C	0.500	0.421	ASTN1
rs6667588	186.60	1.544	33	0.134	0.030	1	G	0.545	0.508	ASTN1
rs6683648	186.63	1.450	23	0.778	0.592	1	A	0.512	0.535	ASTN1
rs12141039	186.66	1.343	30	0.147	0.312	1	T	0.635	0.661	ASTN1
rs982875	186.76	1.458	27	0.059	0.429	1	C	0.528	0.528	FAM5B
rs9425456	186.85	2.453	26	0.243	0.388	1	C	0.503	0.548
rs10732999	186.94	1.953	21	0.007	0.184	1	G	0.719	0.693
rs10913473	187.31	0.662	22	0.194	0.087	1	T	0.547	0.563	LZTR2
rs4650995	187.66	0.560	23	0.986	0.459	1	T	0.555	0.560	C1orf220
rs2816187	187.97	0.469	22	0.408	0.962	1	C	0.614	0.646	ABL2
rs11578278	188.18	0.480	28	0.984	0.632	1	C	0.639	0.673	TDRD5
rs7528949	188.47	0.458	24	0.611	0.635	1	G	0.557	0.540	LHX4
rs3761903	189.08	0.611	30	0.967	0.699	1	C	0.527	0.548	XPR1
rs679931	189.91	0.612	20	0.684	0.711	1	A	0.653	0.650	CACNA1E
rs6700658	190.66	0.465	19	0.791	0.367	1	C	0.557	0.595
rs672527	191.50	0.286	21	0.227	0.910	1	C	0.702	0.701	RNASEL
rs10911232	192.21	0.248	26	0.332	0.098	1	C	0.557	0.599	LAMC1
rs3820691	192.70	0.207	22	0.787	0.410	1	T	0.525	0.524	NCF1
rs732812	193.15	0.206	29	0.557	0.796	1	T	0.532	0.532
rs726427	193.58	0.227	22	0.994	0.453	1	C	0.542	0.598	EDEM3
rs10911704	194.04	0.225	26	0.322	0.386	1	T	0.575	0.598
rs16824765	194.39	0.219	19	0.171	0.433	1	C	0.731	0.701	HMCN1
rs16825295	194.61	0.194	23	0.895	0.867	1	C	0.592	0.602	C1ord27
rs7542180	194.94	0.154	17	0.880	0.866	2	G	0.500	0.480	PLA2G4A

^a1, major allele and 2, minor allele (designation based on NCBI allele frequencies European Caucasians).