Skip to main content
. 2013 Apr 11;9(4):e1002954. doi: 10.1371/journal.pcbi.1002954

Figure 5. Dynamical regime transition in network activity.

Figure 5

(a) Black circles: minimum observed ISI for each active cell in network simulations of different connectivity. Red line: mean of minimum observed ISI across all cells for each network simulation. Synaptic strength parameter Inline graphic so that peak synaptic conductance varies as Inline graphic and peak IPSP size Inline graphic. (b) Same as (a) but versus synaptic strength parameter Inline graphic for connectivity Inline graphic. Actual peak synaptic conductance is given by Inline graphic and Inline graphic generates realistic peak IPSP sizes of around Inline graphic Inline graphic. (c) Green line: mean ISI coefficient of variation (CV) across all cells in network simulations of different connectivity corresponding to (a) (bars indicated sem). Black line: proportion of active cells (those that fire at least three spikes in the 168 second time series). Red line: mean relative entropy, Inline graphic of 100 msec firing rate distribution across all cells rescaled by Inline graphic where Inline graphic is the number of active cells (see text) (bars indicated sem). (d) Same as (c) but corresponding to (b). (a,b,c,d) Inline graphic cell network simulations under constant (randomly fluctuating) excitation without stimulus switching. 180–12 second time series. Inhibitory neurotransmitter timescale Inline graphic msec.