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. 2013 Apr 11;9(4):e1002954. doi: 10.1371/journal.pcbi.1002954

Figure 7. MSN network rate dynamics is marginally stable at striatally relevant connectivity and connection strength.

Figure 7

(a,b) Black circles : proportion of active cells. Red diamonds : mean relative entropy Inline graphic rescaled by Inline graphic where Inline graphic is the number of active cells. Blue crosses : maximal Lyapunov exponent rescaled by 32. Solid lines show three point averages. (a) Variation in connectivity Inline graphic for many simulations. Synaptic strength parameter Inline graphic so that peak synaptic conductance varies as Inline graphic and peak IPSP size as Inline graphic (b) Variation in connection strength Inline graphic for many simulations of connectivity Inline graphic. Actual peak conductance is given by Inline graphic and Inline graphic generates realistic peak IPSP sizes of around Inline graphic Inline graphic. (a,b) Inline graphic cell deterministic reduced rate network simulations (see main text) of length 110 secs. Initial 100 secs discarded from analysis. Inhibitory neurotransmitter timescale Inline graphic msec.