Table 1. Human HLA class I restricted epitopes against pathogenic arenaviruses.
Epitope | Peptide Sequence | MHC I Restriction | Reference(s) |
GTOV | |||
GPC427–435 | GTTSLFLHL | HLA-A2 | [33] |
L1977–1985 | ATVKNVVLR | HLA-A*1101 | [32] |
JUNV | |||
GPC18–26 | ALNIALVAV | HLA-A*0201 | [32] |
LASV | |||
GPC42–50 | GLVGLVTFL | HLA-A*0201 | [27] |
GPC60–68 | SLYKGVYEL | HLA-A*0201 | [26], [27] |
GPC111–120 | SIINHKFCNL | HLA-A*0201 | [32] |
GPC441–449 | YLISIFLHL | HLA-A*0201 | [26], [27] |
LCMV | |||
GPC10–18 | ALPHIIDEV | HLA-A*0201 | [76], [77] |
GPC11–19 | LPHIIDEVI | B*4402 | [77] |
GPC38–46 | FATCGIFAL | B*0702 | [77] |
GPC46–55 | LVSFLLLAGR | HLA-A*1101 | [32] |
GPC112–120 | FTNDSIISH | HLA-A*1101 | [32] |
GPC447–455 | YLVSIFLHL | HLA-A*0201, B*1501 | [76], [77] |
NP45–53 | SEVSNVQRI | B*4402 | [77] |
NP69–77 | SLNQTVHSL | HLA-A*0201 | [76], [77] |
NP246–254 | AAVKAGAAL | B*0702 | [77] |
NP414–422 | KQFKQDSKY | B*1501 | [77] |
Z24–33 | TTYLGPLSCK | HLA-A*1101 | [32] |
Z49–58 | YLCRHCLNLL | HLA-A*0201 | [32], [76], [77] |
MACV | |||
GPC18–26 | ALNIALVAV | HLA-A*0201 | [32] |
GPC444–452 | [33] | ||
NP19–27 | GLSQFTHTV | HLA-A*0201 | [32] |
NP82–90 | SIQKNTIFK | HLA-A*1101 | [32] |
NP432–440 | AMPGVLSYV | HLA-A*0201 | [32] |
Z27–36 | RTAPPSLYGR | HLA-A*1101 | [32] |
Italics, predicted restriction only. GTOV, Guanarito virus; JUNV, Junin virus; LASV, Lassa virus; LCMV, lymphocytic choriomeningitis virus; MACV, Machupo virus.