Table 2. Human HLA class II restricted epitopes against pathogenic arenaviruses.

Epitope	Peptide Sequence	MHC II Restriction	Reference(s)
LASV
GPC236–250	PSPIGYLGLLSQRTR	HLA-DRB1*0101	[78]
GPC241–255	YLGLLSQRTRDIYIS	HLA-DRB1*0101	[78]
GPC282–294	RWMLIEAELKCFG	HLA-DRB	[31]
GPC289–301	ELKCFGNTAVAKC	HLA-DRB	[31]
GPC394–406	LNETHFSDDIEQQ	HLA-DRB	[31]
GPC476–490	SCGLYKQPGVPVRWK	HLA-DRB1*0101	[78]
NP176–188	FGTMPSLTLACLT	HLA-DRB	[79]
NP190–202	QGQVDLNDAVQAL	HLA-DRB	[79]
NP288–300	ALGMFISDTPGER	HLA-DRB	[79]
NP379–391	QLDPNAKTWMDIE	HLA-DRB	[79]
NP498–510	VWDQYKDLCHMHT	HLA-DRB	[79]
GTOV
GPC131–145	KGSPEFDWILGWTIK	HLA-DRB1*0101	[78]
L181–195	DQEYHRLIHSLSKTS	HLA-DRB1*0101	[78]
L391–405	RVLDILVARRLLLKK	HLA-DRB1*0101	[78]
L1826–1840	IQLVFSSMINPLVIT	HLA-DRB1*0101	[78]
NP166–180	KLNNQFGSMPALTIA	HLA-DRB1*0101	[78]
NP191–205	NNVVQALTSLGLLYT	HLA-DRB1*0101	[78]
NP236–250	ISGYNFSLSAAVKAG	HLA-DRB1*0101	[78]
NP541–555	IPIQLLPNTLVFQAK	HLA-DRB1*0101	[78]
JUNV
GPC46–60	FFVFLALAGRSCTEE	HLA-DRB1*0101	[78]
L381–395	VGQMLMLVNDRLLDI	HLA-DRB1*0101	[78]
L391–405	RLLDILEAIKLIRKK	HLA-DRB1*0101	[78]
L411–425	KWVQMCSRTLKNSHQ	HLA-DRB1*0101	[78]
L1491–1505	MFIRNCARKVFNDIK	HLA-DRB1*0101	[78]
L1711–1725	NKNFFWAVKPKAVRQ	HLA-DRB1*0101	[78]
LCMV
GPC66–80	DIYKGVYQFKSVEFD	*0701	[77]
GPC71–85	VYQFKSVEFDMSHLN	*0701	[77]
GPC341–355	HLFKTTVNSLISDQL	*0701	[77]
GPC421–435	LRKDYIKRQGSTPLA	HLA-DRB1*0101	[78]
L256–270	RNFQKVNPEGLIKEF	HLA-DRB1*0101	[78]
L946–960	HLRKVILSEISFHLV	HLA-DRB1*0101	[78]
NP6–20	EVKSFQWTQALRREL	HLA-DRB1*0101	[78]
NP86–100	KNVLKVGRLSAEELM	*1101	[77]
NP106–120	LEKLKAKIMRSERPQ	*0801	[77]
NP236–250	NISGYNFSLGAAVKA	*0701	[77]
NP261–275	LESILIKPSNSEDLL	*0701	[77]
NP281–295	AKRKLNMFVSDQVGD	*0701	[77]
NP311–325	EGWPYIACRTSIVGR	*0701	[77]
NP356–370	VGLSYSQTMLLKDLM	*0701	[77]
NP411–425	VDQKQFKQDSKYSHG	*0701	[77]
NP521–535	MDCIIFESASKARLP	HLA-DRB1*0101, *0801	[77], [78]
MACV
GPC96–110	NSFYYMKGGVNTFLI	HLA-DRB1*0101	[78]
GPC251–265	SKTHLNFERSLKAFF	HLA-DRB1*0101	[78]
GPC446–460	ASLFLHLVGIPTHRH	HLA-DRB1*0101	[78]
L391–405	DRVLDILEAVKLIRK	HLA-DRB1*0101	[78]
L636–650	RYFLMAFANQIHHID	HLA-DRB1*0101	[78]
L866–880	DYLILKNLTGLVSAG	HLA-DRB1*0101	[78]
L1491–1505	TSFIRNCARKVFNDI	HLA-DRB1*0101	[78]
L1711–1725	NNQNFFWAVKPKVVR	HLA-DRB1*0101	[78]
NP191–205	NSVVQALTSLGLLYT	HLA-DRB1*0101	[78]
Z21–35	PSAEFRRTAPPSLYG	HLA-DRB1*0101	[78]

Italics, predicted restriction only. GTOV, Guanarito virus; JUNV, Junin virus; LASV, Lassa virus; LCMV, lymphocytic choriomeningitis virus; MACV, Machupo virus.