Table 3.
Description of outcome measures used
| Author, yr 6MWT | OM procedure referenced | Encouragement standardised | Number of repeat Ax in testing session | ||||
|---|---|---|---|---|---|---|---|
| Jones 2012
[40] | Yes
[50] |  | NR |  | NR |  |  | 
| Pancieri 2010
[22] | No |  | ‘encouraged walking’ | NR |  |  | |
| Kasymjanova 2009
[25] | Yes
[50,67] |  | NR |  | 1 x practice 1 x actual (on different days) |  | |
| Mao 2007, Miller 2005
[26,27] | Yes
[20] |  | NR |  | NR |  |  | 
| Saad 2007
[24] | Yes
[50] |  | NR |  | NR |  |  | 
| Parsons 2003
[39] | Yes
[34,68-72] |  | Yes |  | 1 x practice, 1 x actual |  | |
| Pierce 1994
[23] | Yes [73] |  | NR |  | 3 (best value used) |  | |
| Holden 1992
[41] | No |  | NR |  | 2 (15-30 min interval) |  | |
| ISWT | OM procedure referenced |  | Encouragement standardised |  | No of repeat Ax in testing session |  | Additional description | 
| England 2012
[44] | Yes
[59] |  | NR |  | 1 x practice, 1 x actual |  | Participants wore COSMED K4 b2 system (COSMED, Italy) to measure HR, VE and VO2 throughout test | 
| Win 2006; 2004
[30,64] | Yes
[59] |  | NR |  | 1 |  | HR and SpO2 monitored and recorded at 30 second intervals throughout test | 
| SCT | Equipment | Monitoring during test | Intensity | Outcome | Number of repeat Ax in testing session | Experience of assessors | Additional description | 
| Brunelli 2012, 2010, 2008a, 2008b, 2007, 2005, 2004, 2003, 2002 [20–21, 31, 32–35, 42–43,] | 16 flights x 11 steps (0.155 m height) | Continuous verbal interaction to Ax SOB/ symptoms; HR; SpO2 | Pace of pt choice, asked to climb max no steps and stop for exhaustion, limiting SOB, leg fatigue or chest pain | No steps and time taken, minimum value SpO2, exercise oxygen desaturation (= fall SpO2 < 90% or fall >4%) | 1 | Physician | Calculations from test: | 
|  |  |  |  |  |  |  | • Work = (step height in meters x steps per min x body weight in kg x 0.1635)[74] | 
|  |  |  |  |  |  |  | • VO2max (ml/min) = 5.8 x weight in kg + 151 + 10.1 x work) [74] | 
|  |  |  |  |  |  |  | • VO2max corrected for body surface area (ml/min2) = VO2max / max HR | 
| Pancieri 2010
[22] | 6 flights x 12 steps (16.9 cm height), 30° incline | HR, SpO2 | Climb all steps in the shortest possible time with verbal encouragement between flights. Testing stopped for fatigue, limiting SOB, thoracic pain or exhaustion | Time taken | 1 |  |  | 
| Koegelenberg 2008
[29] | 12 flights x 10 steps (3.48 m b/t floors) | HR, SpO2 | Pt asked to climb ‘as fast and as high’ as they possibly could to a max elevation of 20 m | Altitude, time taken, speed of ascent | NR | NR | Stair climb considered completed if pt rested or more than 3 seconds or reached 20 m height Allowed to use rail only for balance | 
| Nikolic 2008
[36] | 92 steps (0.15 m height) | HR, SpO2 (measured every 20 steps) | Pace of pt choice, asked to climb max no steps and stop for exhaustion, limiting SOB, leg fatigue or chest pain | No steps, time taken | 1 | Physician | Pt instructed not to use hand-rail | 
| Toker 2007
[37] | 20 steps per flight (15 cm height) | HR, SpO2 | Pt motivated to do their best and motivation | SpO2 (pre, post, change), HR (pre, post, change), time taken | 2 | Resident doctor |  | 
| Pate 1996
[38] | 21 steps per flight (17.5 cm height) | HR, SpO2 | Moderate pace of pts choice, encouraged to exercise to a symptom-limited max and complete the flight of stairs they were on if possible | No steps, time taken, altitude (m), reason for stopping | 1 | NR | Test considered completed as soon as patient stopped for any reason Pt instructed not to use hand-rail | 
| Holden 1992
[41] | 11 steps per flight (0.17 m height) | SpO2 | Own pace | Altitude, time taken | 1 | Therapist | Calculations from test: | 
|  |  |  |  |  |  |  | • Work = step height x steps per min x weight in kg x 0.1635 | 
|  |  |  |  |  |  |  | • VO2 ml/min = 5.8 x weight in kg + 151 + (10.1 x work) | 
| Physical activity | Equipment |  | Location of monitoring | Outcome | Duration of Ax | Position of sensor |  | 
| Maddocks 2012
[47] | Uni-axial accelerometer ActivPALTM monitor (PAL Technologies Ltd., UK) | Home environment | Mean daily step count, number of sit-to-stand transitions, time in hrs spent sitting/lying, upright standing and upright stepping | 7 days (6 full days of data) | Mid-third of anterior thigh of pts chosen leg |  |  | 
| Grutsch 2011a, 2011b; Du-Quiton 2010
[48-50] | Actigraph Piezoelectric Accelerometer (Ambulatory Monitoring Inc., AMI, USA) | Group 1 (inpt) and group 2 (home environment) | Mean duration daytime activity (no of vertical/horizontal accelerations per min) | 3-7 days | Non-dominant wrist |  |  | 
| Novoa 2011
[51] | OMROM Walking Style Pro® pedometer | Home environment | Mean daily no total and aerobic steps; mean daily distance walked (km); mean daily time of aerobic activity (min) | Daytime only, daily Ax while waiting for surgery | Pedometer attached to waist band or belt |  |  | 
| Maddocks 2010
[46] | Uni-axial accelerometer ActivPALTM monitor (PAL Technologies Ltd., UK) | Home environment | Mean daily step count and estimate energy expenditure (METh); acceptability (non-compliance in hours); optimal duration of monitoring | 7 days (6 full days of data) | Mid-third of anterior thigh of dominant leg |  |  | 
| Physical activity | Equipment |  | Location of monitoring | Outcome | Duration of Ax | Position of sensor |  | 
| Maddocks 2012
[47] | Uni-axial accelerometer ActivPALTM monitor (PAL Technologies Ltd., UK) | Home environment | Mean daily step count, number of sit-to-stand transitions, time in hrs spent sitting/lying, upright standing and upright stepping | 7 days (6 full days of data) | Mid-third of anterior thigh of pts chosen leg |  |  | 
| Grutsch 2011a, 2011b; Du-Quiton 2010
[48-50] | Actigraph Piezoelectric Accelerometer (Ambulatory Monitoring Inc., AMI, USA) | Group 1 (inpt) and group 2 (home environment) | Mean duration daytime activity (no of vertical/horizontal accelerations per min) | 3-7 days | Non-dominant wrist |  |  | 
| Novoa 2011
[51] | OMROM Walking Style Pro® pedometer | Home environment | Mean daily no total and aerobic steps; mean daily distance walked (km); mean daily time of aerobic activity (min) | Daytime only, daily Ax while waiting for surgery | Pedometer attached to waist band or belt |  |  | 
| Maddocks 2010
[46] | Uni-axial accelerometer ActivPALTM monitor (PAL Technologies Ltd., UK) | Home environment | Mean daily step count and estimate energy expenditure (METh); acceptability (non-compliance in hours); optimal duration of monitoring | 7 days (6 full days of data) | Mid-third of anterior thigh of dominant leg |  |  | 
| Muscle strength | Equipment | Muscle group movement | Participant position | No of assessors | Number of repeat Ax in testing session | Experience of assessors | Additional description | 
| Trutschnigg 2008
[28] | Jamar HGD (Sammons Preston, Bolingbrook), position 3 on handle | Grip | Sitting, feet on ground shoulder width apart, Elb 90 ° F, wrist 0°, arm on arm rest [75] | NR | 1-2 x practice 2 x 3reps actual (mean value used) | NR | Dominant hand Patient instructed when to start and stop contraction with a 3 second contraction time No encouragement | 
| Brown 2005
[53] | Square design chair with firm seat 43 cm height and arm rests | Sit to stand | Seated | NR | NR | NR | Pt asked to rise from seated position to fully upright position as fast as they could, if possible without using arm rests | 
| Knols 2002
[52] | Mecmesin FB50K pull-gauge HHD, Mecmesin, England | Elb E, Knee E | 1. Supine, Elb 90 °F, upper edge pull- attachment perpendicular to ulnar side of forearm distal to caput ulnae, non-elastic belt over ASIS stabilised pt on table | 2 (random order) 30 min interval | 6 x practice 3 x actual (60 second interval) | Physiotherapist | Dominant UL and LL Ax – identified by asking participant to throw a ball and kick a ball (preferred stance leg chosen) Figures also provided for both testing positions ‘Make’ test used Pt asked to increase force over 2 seconds and maintain for another 5 seconds | 
| 2. sitting edge of table upright no back support, knee 90 °F, stabilise trunk by grasping table, lower edge pull-attachment perpendicular to ant surface tibia, distal to end med mall | 
Abbreviations: 1RM, one repetition maximum; 6MWT, six-minute walk test; ant, anterior; ASIS, spinae iliacae ant superiorum; ATS, American Thoracic Society; Ax, assessment; bt, between; cm, centimeters; dyn, dynamometer; E, extension; Elb, elbow; F, flexion; HHD, hand held dynamometer; HGD, hand grip dynamometer; HR, heart rate; hrs, hours; ISWT, incremental shuttle walk test; kg, kilograms; km, kilometers; L, left; LL, lower limb; m, meters; mal, malleolus; max, maximum; med, medial; METh, metabolic equivalent hours; min, minutes; ml, millimetres; NA, not applicable; no, number; NR, not reported; OM, outcome measure; pt, participant; R, right; reps, repetitions; SCT, stair-climb test; SOB, shortness of breath; SpO2, oxygen saturation; UL, upper limb; VE, minute ventilation; VO2 oxygen uptake; VO2max; maximal oxygen consumption; yr, year published.