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. 2013 Mar 20;13:135. doi: 10.1186/1471-2407-13-135

Table 3.

Description of outcome measures used

Author, yr
6MWT
OM procedure referenced   Encouragement standardised   Number of repeat Ax in testing session    
Jones 2012 [40]
Yes [50]
 
NR
 
NR
 
 
Pancieri 2010 [22]
No
 
‘encouraged walking’
  NR
 
 
Kasymjanova 2009 [25]
Yes [50,67]
 
NR
 
1 x practice 1 x actual (on different days)
   
Mao 2007, Miller 2005 [26,27]
Yes [20]
 
NR
 
NR
 
 
Saad 2007 [24]
Yes [50]
 
NR
 
NR
 
 
Parsons 2003 [39]
Yes [34,68-72]
 
Yes
 
1 x practice, 1 x actual
   
Pierce 1994 [23]
Yes [73]
 
NR
 
3 (best value used)
   
Holden 1992 [41]
No
 
NR
 
2 (15-30 min interval)
   
ISWT
OM procedure referenced
 
Encouragement standardised
 
No of repeat Ax in testing session
 
Additional description
England 2012 [44]
Yes [59]
 
NR
 
1 x practice, 1 x actual
 
Participants wore COSMED K4 b2 system (COSMED, Italy) to measure HR, VE and VO2 throughout test
Win 2006; 2004 [30,64]
Yes [59]
 
NR
 
1
 
HR and SpO2 monitored and recorded at 30 second intervals throughout test
SCT
Equipment
Monitoring during test
Intensity
Outcome
Number of repeat Ax in testing session
Experience of assessors
Additional description
Brunelli 2012, 2010, 2008a, 2008b, 2007, 2005, 2004, 2003, 2002 [20–21, 31, 32–35, 42–43,]
16 flights x 11 steps (0.155 m height)
Continuous verbal interaction to Ax SOB/ symptoms; HR; SpO2
Pace of pt choice, asked to climb max no steps and stop for exhaustion, limiting SOB, leg fatigue or chest pain
No steps and time taken, minimum value SpO2, exercise oxygen desaturation (= fall SpO2 < 90% or fall >4%)
1
Physician
Calculations from test:
 
 
 
 
 
 
 
• Work = (step height in meters x steps per min x body weight in kg x 0.1635)[74]
 
 
 
 
 
 
 
• VO2max (ml/min) = 5.8 x weight in kg + 151 + 10.1 x work) [74]
 
 
 
 
 
 
 
• VO2max corrected for body surface area (ml/min2) = VO2max / max HR
Pancieri 2010 [22]
6 flights x 12 steps (16.9 cm height), 30° incline
HR, SpO2
Climb all steps in the shortest possible time with verbal encouragement between flights. Testing stopped for fatigue, limiting SOB, thoracic pain or exhaustion
Time taken
1
 
 
Koegelenberg 2008 [29]
12 flights x 10 steps (3.48 m b/t floors)
HR, SpO2
Pt asked to climb ‘as fast and as high’ as they possibly could to a max elevation of 20 m
Altitude, time taken, speed of ascent
NR
NR
Stair climb considered completed if pt rested or more than 3 seconds or reached 20 m height Allowed to use rail only for balance
Nikolic 2008 [36]
92 steps (0.15 m height)
HR, SpO2 (measured every 20 steps)
Pace of pt choice, asked to climb max no steps and stop for exhaustion, limiting SOB, leg fatigue or chest pain
No steps, time taken
1
Physician
Pt instructed not to use hand-rail
Toker 2007 [37]
20 steps per flight (15 cm height)
HR, SpO2
Pt motivated to do their best and motivation
SpO2 (pre, post, change), HR (pre, post, change), time taken
2
Resident doctor
 
Pate 1996 [38]
21 steps per flight (17.5 cm height)
HR, SpO2
Moderate pace of pts choice, encouraged to exercise to a symptom-limited max and complete the flight of stairs they were on if possible
No steps, time taken, altitude (m), reason for stopping
1
NR
Test considered completed as soon as patient stopped for any reason Pt instructed not to use hand-rail
Holden 1992 [41]
11 steps per flight (0.17 m height)
SpO2
Own pace
Altitude, time taken
1
Therapist
Calculations from test:
 
 
 
 
 
 
 
• Work = step height x steps per min x weight in kg x 0.1635
 
 
 
 
 
 
 
• VO2 ml/min = 5.8 x weight in kg + 151 + (10.1 x work)
Physical activity
Equipment
 
Location of monitoring
Outcome
Duration of Ax
Position of sensor
 
Maddocks 2012 [47]
Uni-axial accelerometer ActivPALTM monitor (PAL Technologies Ltd., UK)
Home environment
Mean daily step count, number of sit-to-stand transitions, time in hrs spent sitting/lying, upright standing and upright stepping
7 days (6 full days of data)
Mid-third of anterior thigh of pts chosen leg
 
 
Grutsch 2011a, 2011b; Du-Quiton 2010 [48-50]
Actigraph Piezoelectric Accelerometer (Ambulatory Monitoring Inc., AMI, USA)
Group 1 (inpt) and group 2 (home environment)
Mean duration daytime activity (no of vertical/horizontal accelerations per min)
3-7 days
Non-dominant wrist
 
 
Novoa 2011 [51]
OMROM Walking Style Pro® pedometer
Home environment
Mean daily no total and aerobic steps; mean daily distance walked (km); mean daily time of aerobic activity (min)
Daytime only, daily Ax while waiting for surgery
Pedometer attached to waist band or belt
 
 
Maddocks 2010 [46]
Uni-axial accelerometer ActivPALTM monitor (PAL Technologies Ltd., UK)
Home environment
Mean daily step count and estimate energy expenditure (METh); acceptability (non-compliance in hours); optimal duration of monitoring
7 days (6 full days of data)
Mid-third of anterior thigh of dominant leg
 
 
Physical activity
Equipment
 
Location of monitoring
Outcome
Duration of Ax
Position of sensor
 
Maddocks 2012 [47]
Uni-axial accelerometer ActivPALTM monitor (PAL Technologies Ltd., UK)
Home environment
Mean daily step count, number of sit-to-stand transitions, time in hrs spent sitting/lying, upright standing and upright stepping
7 days (6 full days of data)
Mid-third of anterior thigh of pts chosen leg
 
 
Grutsch 2011a, 2011b; Du-Quiton 2010 [48-50]
Actigraph Piezoelectric Accelerometer (Ambulatory Monitoring Inc., AMI, USA)
Group 1 (inpt) and group 2 (home environment)
Mean duration daytime activity (no of vertical/horizontal accelerations per min)
3-7 days
Non-dominant wrist
 
 
Novoa 2011 [51]
OMROM Walking Style Pro® pedometer
Home environment
Mean daily no total and aerobic steps; mean daily distance walked (km); mean daily time of aerobic activity (min)
Daytime only, daily Ax while waiting for surgery
Pedometer attached to waist band or belt
 
 
Maddocks 2010 [46]
Uni-axial accelerometer ActivPALTM monitor (PAL Technologies Ltd., UK)
Home environment
Mean daily step count and estimate energy expenditure (METh); acceptability (non-compliance in hours); optimal duration of monitoring
7 days (6 full days of data)
Mid-third of anterior thigh of dominant leg
 
 
Muscle strength
Equipment
Muscle group movement
Participant position
No of assessors
Number of repeat Ax in testing session
Experience of assessors
Additional description
Trutschnigg 2008 [28]
Jamar HGD (Sammons Preston, Bolingbrook), position 3 on handle
Grip
Sitting, feet on ground shoulder width apart, Elb 90 ° F, wrist 0°, arm on arm rest [75]
NR
1-2 x practice 2 x 3reps actual (mean value used)
NR
Dominant hand Patient instructed when to start and stop contraction with a 3 second contraction time No encouragement
Brown 2005 [53]
Square design chair with firm seat 43 cm height and arm rests
Sit to stand
Seated
NR
NR
NR
Pt asked to rise from seated position to fully upright position as fast as they could, if possible without using arm rests
Knols 2002 [52]
Mecmesin FB50K pull-gauge HHD, Mecmesin, England
Elb E, Knee E
1. Supine, Elb 90 °F, upper edge pull- attachment perpendicular to ulnar side of forearm distal to caput ulnae, non-elastic belt over ASIS stabilised pt on table
2 (random order) 30 min interval
6 x practice 3 x actual (60 second interval)
Physiotherapist
Dominant UL and LL Ax – identified by asking participant to throw a ball and kick a ball (preferred stance leg chosen) Figures also provided for both testing positions ‘Make’ test used Pt asked to increase force over 2 seconds and maintain for another 5 seconds
      2. sitting edge of table upright no back support, knee 90 °F, stabilise trunk by grasping table, lower edge pull-attachment perpendicular to ant surface tibia, distal to end med mall        

Abbreviations: 1RM, one repetition maximum; 6MWT, six-minute walk test; ant, anterior; ASIS, spinae iliacae ant superiorum; ATS, American Thoracic Society; Ax, assessment; bt, between; cm, centimeters; dyn, dynamometer; E, extension; Elb, elbow; F, flexion; HHD, hand held dynamometer; HGD, hand grip dynamometer; HR, heart rate; hrs, hours; ISWT, incremental shuttle walk test; kg, kilograms; km, kilometers; L, left; LL, lower limb; m, meters; mal, malleolus; max, maximum; med, medial; METh, metabolic equivalent hours; min, minutes; ml, millimetres; NA, not applicable; no, number; NR, not reported; OM, outcome measure; pt, participant; R, right; reps, repetitions; SCT, stair-climb test; SOB, shortness of breath; SpO2, oxygen saturation; UL, upper limb; VE, minute ventilation; VO2 oxygen uptake; VO2max; maximal oxygen consumption; yr, year published.