Table 3.
Characteristics of PROQOL participants
| Variables | ALL | Not on Rx | NNRTI | PI | p-value |
|---|---|---|---|---|---|
| |
N = 102 |
N = 15 |
N = 46 |
N = 41 |
|
|
Female |
15 (14.7%) |
4 (26.7%) |
7 (15.2%) |
4 (9.8%) |
p=0.3 |
|
Age |
46 (37–53.8) |
41 (32.5-49.5) |
48 (37–56.5) |
45 (40–53) |
p=0.4 |
|
Transmission |
|
|
|
|
p=0.08 |
|
Heterosexual/other |
42 (41.2%) |
10 (66.7%) |
21 (45.7%) |
11 (26.8%) |
|
|
IDU |
6 (5.9%) |
0 (0%) |
3 (6.5%) |
3 (7.3%) |
|
|
MSM |
54 (52.9%) |
5 (33.3%) |
22 (47.8%) |
27 (65.9%) |
|
|
Married |
34 (33.3%) |
5 (33.3%) |
17 (37%) |
12 (29.3%) |
p=0.7 |
|
Caucasian |
80 (78.4%) |
9 (60%) |
37 (80.4%) |
34 (82.9%) |
p=0.2 |
|
Living alone |
40 (39.2%) |
8 (53.3%) |
16 (34.8%) |
16 (39%) |
p=0.5 |
|
Post-secondary |
37 (36.3%) |
6 (40%) |
17 (37%) |
14 (34.1%) |
p=0.9 |
|
Unemployed/sickness benefits |
18 (17.6%) |
2 (13.3%) |
3 (6.5%) |
13 (31.7%) |
p=0.007 |
|
Smoker ≥ 2 cigarettes/day |
41 (40.2%) |
4 (26.7%) |
19 (41.3%) |
18 (43.9%) |
p=0.0002 |
|
Alcohol ≥ 2 glasses/day |
15 (14.7%) |
1 (6.7%) |
7 (15.2%) |
7 (17.1%) |
p=0.5 |
|
Diagnosed < 2 years |
16 (15.7%) |
8 (53.3%) |
6 (13%) |
2 (4.9%) |
p=0.7 |
|
Time since diagnosis (years) |
7.3 (2.9-15.6) |
1.5 (0.8-3.8) |
6.8 (3.2-11.9) |
13.2 (6.2-18.9) |
p<0.0001 |
|
Body mass index |
24.3 (22–28) |
23.6 (22–28) |
25.4 (23–28) |
23.9 (22–27) |
p=0.5 |
|
CD4 T cells |
530 (376–733) |
546 (512–695) |
591 (386–853) |
455 (323–638) |
p=0.1 |
|
Undetectable VL |
77 (75.5%) |
2 (13.3%) |
43 (93.5%) |
32 (78%) |
p<0.0001 |
|
Time on ART (years) |
4.2 (0.8-11.8) |
- |
4.4 (2.1-9.9) |
10.7 (3.2-13.6) |
p<0.0001 |
|
On non-ART medication |
38 (37.3%) |
3 (20%) |
15 (32.6%) |
20 (48.8%) |
p=0.1 |
|
ART pill burden (tablets/day) |
3 (2–5) |
- |
2.5 (2–3) |
4 (3–5) |
p<0.0001 |
|
Non-adherent to ART |
18 (17.6%) |
- |
7 (15.2%) |
11 (26.8%) |
p=0.2 |
|
Depressive |
26 (25.5%) |
3 (20%) |
8 (17.4%) |
15 (36.6%) |
p=0.1 |
|
Other comorbidity |
56 (54.9%) |
8 (53.3%) |
20 (43.5%) |
28 (68.3%) |
p=0.07 |
|
Sexual dysfunction |
25 (24.5%) |
4 (26.7%) |
9 (19.6%) |
12 (29.3%) |
p=0.5 |
| Number symptoms (total) | 5 (2–10) | 4 (1–10.5) | 5 (1–8) | 8 (5–12) | p=0.01 |
For categorical variables, values are N(%) and the p-value corresponds to a Fisher exact test of equal proportions across treatment groups; for continuous variables, values are median (interquartile range) with the p-values reflecting differences across the treatment groups as assessed by a Kruskal-Wallis test.