Figure 1. Definitions of domain boundaries and hinge regions.

The red represents boundary, the green represents domain. A residue assigned to the boundary is coded with “1″; A residue assigned to the hinge region is coded with “2″; otherwise, “0″. A hinge region contains 2*R (for example, R = 10) residues that are centrally located at the N- and C-terminus of a domain and bidirectionally extended into the domain and the boundary R residues.